In Ehlers-Danlos syndrome, similar to Marfan’s, patients may exhibit what condition?

In Ehlers-Danlos syndrome, individuals may exhibit mitral valve prolapse due to the connective tissue abnormalities characteristic of the condition. Both Ehlers-Danlos syndrome and Marfan syndrome involve defects in collagen and other connective tissues, which can lead to structural changes in the heart and other organs.

Mitral valve prolapse occurs when the valve leaflets are elongated or distorted, allowing them to bulge backward into the left atrium during ventricular contraction. The weakened connective tissue in patients with Ehlers-Danlos syndrome makes them more susceptible to this condition. Such structural deformities can compromise the normal function of the heart, leading to potential complications, including arrhythmias or valvular insufficiency.

Cardiac ischemia, aortic stenosis, and heart failure can result from various other conditions and complexities but are not specifically associated with the typical structural changes observed in Ehlers-Danlos syndrome as mitral valve prolapse is. As a result, the representative link to Ehlers-Danlos syndrome most clearly is found in mitral valve prolapse.